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The University of Pittsburgh Medical Center (UPMC) won’t require its health care employees to take the upcoming COVID-19 vaccine, which the medical provider expects to begin offering as soon as this month, according to PennLive.. For starters, general uncertainty over the vaccine. And while the $21 billion nonprofit organization (which employs 89,000 people) has a mandatory flu vaccination policy, it’s “based on decades of experience with the influenza vaccine.